In 1947 Asimov was engaged in doctoral research in chemistry and, as part of his experimental procedure, he needed to dissolve catechol in water. The nature of the hydrocarbon nucleus is unknown, although it seems in part to be an aromatic hydrocarbon. Thiotimoline is derived from the bark of the (fictitious) shrub Rosacea karlsbadensis rufo, and the thiotimoline molecule includes at least fourteen hydroxy groups, two amino groups, and one sulfonic acid group, and possibly one nitro compound group as well. In Asimov's writings the endochronicity of thiotimoline is explained by the fact that in the thiotimoline molecule, there is at least one carbon atom such that, while two of the carbon's four chemical bonds lie in normal space and time, one of the bonds projects into the future and another into the past. The major peculiarity of the chemical is its "endochronicity": it starts dissolving before it makes contact with water.Īsimov went on to write three additional short stories, each describing different properties or uses of thiotimoline. It was first described in a spoof scientific paper titled "The Endochronic Properties of Resublimated Thiotimoline" in 1948. Thiotimoline is a fictitious chemical compound conceived by American biochemist and science fiction author Isaac Asimov. The Micropsychiatric Applications of Thiotimoline Fictional organic compound from short stories by Isaac Asimov The Endochronic Properties of Resublimated Thiotimoline
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